Pdes as modifiers of the igfr pathway and methods of use

Details Pdes as modifiers of the igfr pathway and methods of use Pdes as modifiers of the igfr pathway and methods of use

G - Physics

01

N

G01N 33/53 (2006.01) C12N 15/00 (2006.01) G01N 33/536 (2006.01)

Patent

CA 2559543

Human PDE genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of PDE are provided

L'invention concerne des gènes PDE humains identifiés en tant que modulateurs de la voie IGFR, qui sont par conséquent utiles en tant que cibles thérapeutiques pour des troubles associés à une fonction IGFR défaillante. L'invention concerne des méthodes pour identifier des modulateurs de IGFR. Ces méthodes consistent à cribler des agents modulant l'activité de PDE.

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