Pepsin inhibition by alginates

Details Pepsin inhibition by alginates Pepsin inhibition by alginates

A - Human Necessities

61

K

A61K 31/715 (2006.01) A61K 31/734 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2410013

Certain alginates exhibit a superior ability to inhibit the proteolytic activity of pepsin and/or gastric juice. In particular, alginates having a molecular weight between 40,000 and 350,000 exhibit a superior inhibition of the proteolytic activity of pepsin and gastric juice by over 50 % when measured using an N-terminal assay.

Certains alginates possèdent une capacité supérieure d'inhibition de l'activité protéolytique de la pepsine et/ou du suc gastrique. En particulier, les alginates présentant un poids moléculaire compris entre 40000 et 35000 possèdent une capacité supérieure d'inhibition de l'activité protéolytique de la pepsine et du suc gastrique, de plus de 50 %, mesurée à l'aide d'un dosage de groupes N terminaux.

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