Peptide-coated implants and processes for their preparation

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/34 (2006.01) A61L 27/10 (2006.01) A61L 27/38 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01)

Patent

CA 2290481

The invention describes the possibility of the biofunctionalization of biomaterials, in particular implants, by their made-to-measure coating with synthesized cell- or tissue-selective RGD peptides which in vitro stimulate the adhesion of mainly those cell species which in each case are intended to accomplish the tissue integration of the appropriate biomaterial.

L'invention concerne la possibilité de biofonctionnaliser des biomatériaux, notamment des implants, par leur recouvrement à la demande avec des peptides RGD à sélectivité cellulaire ou tissulaire synthétisés, qui stimulent in vitro l'adhérence essentiellement des espèces cellulaires destinées à effectuer dans chaque cas l'intégration tissulaire du biomatériau correspondant.

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