A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 49/00 (2006.01)
Patent
CA 2685553
The present invention relates to labelled cMet binding peptides suitable for optical imaging in vivo. The peptides are labelled with an optical reporter group suitable for imaging in the red to near-infrared region. Also disclosed are pharmaceutical compositions and kits, as well as in vivo imaging methods, especially of use in the detection, staging, diagnosis, monitoring of disease progression or monitoring of treatment of colorectal cancer (CRC).
La présente invention porte sur des peptides de liaison à cMet marqués, appropriés pour une imagerie optique in vivo. Les peptides sont marqués avec un groupe reporteur optique approprié pour une imagerie dans la région rouge ou proche infrarouge. L'invention concerne également des compositions pharmaceutiques et des coffrets, ainsi que des procédés d'imagerie in vivo, notamment utile dans la détection, la stadification, le diagnostic, la surveillance de la progression d'une maladie ou la surveillance d'un traitement du cancer colorectal (CRC).
Cuthbertson Alan
Johannesen Edvin Wilhelm
Fetherstonhaugh & Co.
Ge Healthcare As
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