A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4152 (2006.01) A61K 9/70 (2006.01) A61K 47/10 (2006.01) A61K 47/30 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2504873
The present invention relates to a percutaneous absorption preparation (which may also be in the form of an adhesive preparation) containing, as an active ingredient, 0.1 to 30 percent by mass of 3-methyl-1-phenyl-2-pyrazolin-5-one represented by the following formula: (see above formula) or a medically acceptable salt thereof in an appropriate base such as an aqueous base or a rubber base. This preparation (or adhesive preparation) is an excellent percutaneous absorption preparation (or percutaneous absorption adhesive preparation) which has good percutaneous absorbability of the active ingredient and causes little skin irritation.
La présente invention a trait à des préparations d'absorption percutanée (éventuellement sous forme de bandes adhésives) contenant en tant que principe actif de 0,1 à 30 % en poids de 3-méthyl-1-phényl-2-pyrazolin-5-one répondant à la formule (I) ou à un de ses sels pharmaceutiquement acceptables dans un excipient approprié, par exemple, un support aqueux ou un support en caoutchouc. Ces préparations (ou bandes adhésives) sont d'excellentes préparations d'absorption percutanée (des bandes adhésives d'absorption percutanée) présentant une absorbabilité percutanée élevée du principe actif et peu d'irritation cutanée.
Hashitani Hitomi
Horiuchi Tamaki
Mori Jun
Shimada Shingo
Waki Hitomi
Lead Chemical Co. Ltd.
Mccarthy Tetrault Llp
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