Pharmaceutical composition and procedure to treat and...

A - Human Necessities – 61 – K

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A61K 36/889 (2006.01) A61P 13/08 (2006.01)

Patent

CA 2519410

The invention relates to a novel pharmaceutical composition and to the method of producing same from the fruits of the royal palm (Roystonea regia) in order to prevent and/or treat benign prostatic hyperplasia (BPH) and prostatitis as well as alopecia and hirsutism. The inventive composition comprises a mixture of free fatty acids and/or the esters thereof, within a range of between 8 and 28 carbon atoms, in particular between 8 and 18 carbon atoms, and, more specifically, saturated straight--chain free fatty acids with 8, 10, 12, 14, 16 and 18 carbon atoms and mono- unsaturated free fatty acids with 16:1 and 18:1 carbon atoms. The inventive method of producing the aforementioned composition comprises the drying and crushing of the fruits, with optional basic hydrolysis, and, subsequently, selective extraction in organic solvents.

L'invention se rapporte à l'obtention d'une nouvelle composition pharmaceutique et à son procédé d'obtention à partir des fruits du palmier royal (roystonea regia) afin de prévenir et/ou traiter l'hyperplasie prostatique bénigne (HPB) et la prostatite, ainsi que l'alopécie et l'hirsutisme. La composition renferme un mélange d'acides gras libres et/ou leurs esters comprenant entre 8 et 28 atomes de carbone, plus particulièrement entre 8 et 18 atomes de carbone et plus spécifiquement ceux saturés à chaîne linéaire ayant 8, 10, 12, 14, 16 et 18 atomes de carbone et les monoinsaturés de 16 :1 et 18 :1 atomes de carbone. Cette composition est obtenue au moyen d'un procédé au cours duquel on sèche et broie les fruits qui sont soumis ou non à hydrolyse de base puis on effectue une extraction sélective dans des solvants organiques.

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