C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/5377 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 409/14 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2683619
The invention provides a compound which is a pyrimidine of formula (I): The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
La présente invention concerne un composé qui est une pyrimidine de formule (I). Les composés sont inhibiteurs de PI3K et peuvent donc être utilisés pour traiter des maladies et des troubles provoqués par une croissance cellulaire anormale, une fonction ou un comportement associé(e) à la PI3 kinase tels que le cancer, des troubles immunitaires, une maladie cardiovasculaire, une infection virale, l'inflammation, des troubles de la fonction métabolique/endocrinienne et des troubles neurologiques.
Baker Stewart James
Dechaux Elsa Amandine
Goldsmith Paul John
Hancox Timothy Colin
Krintel Sussie Lerche
F. Hoffmann-La Roche Ag
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Institute Of Cancer Research: Royal Cancer Hospital
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