Pharmaceutical formulations and methods for treating...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2754680

The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.

La présente invention concerne des compositions pharmaceutiques destinées au traitement d'une infection des voies respiratoires ou d'une maladie pulmonaire chez un individu. Lesdites compositions comprennent un sel de calcium et un sel de sodium, le rapport entre Ca2+ et Na+ étant compris entre environ 4 à 1 (mole/mole) et environ 16 à 1 (mole/mole). L'invention concerne également des méthodes de traitement (y compris des méthodes de traitement prophylactique) et de réduction de la transmission d'une infectiondes voies respiratoires, des méthodes de traitement (y compris des méthodes de traitement prophylactique) d'une maladie pulmonaire ou d'une aggravation aiguë d'une maladie pulmonaire, ainsi que des méthodes de réduction de la progression d'une aggravation aiguë d'une maladie pulmonaire, cela comprenant l'administration d'une composition pharmaceutique comprenant un sel de calcium et un sel de sodium.

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