Phenyl and heterocyclic tetrahydropyridyl and piperazinyl...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) C07D 209/34 (2006.01) C07D 215/20 (2006.01) C07D 217/02 (2006.01) C07D 235/06 (2006.01) C07D 307/79 (2006.01) C07D 307/83 (2006.01) C07D 311/22 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1280750

CDDG010686 PD-3469-1 ABSTRACT Novel phenyl and heterocyclic tetrahydropyridyl and piperazinyl alkoxy benzheterocyclic compounds are described which have valuable neuroleptic properties by virtue of their dopamine autoreceptor agonist activity. Methods of preparation, pharmaceutical compositions, and methods for treating psychoses, such as schizophrenia, are also described. The novel compounds have the general formula: Image wherein n, A, X and Het are as defined in the disclosure and claims.

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