Phenyl-furan compounds as vitamin d receptor modulators

Details Phenyl-furan compounds as vitamin d receptor modulators Phenyl-furan compounds as vitamin d receptor modulators

C - Chemistry, Metallurgy

07

D

C07D 307/68 (2006.01) A61K 31/341 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2546729

The present invention relates to novel, non-secosteroidal, phenyl-furan compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.

L'invention porte sur de nouveaux composés non sécostéroïdaux de phényl-furane s'avérant moins hypercalcémiant que la 1?,25dihydroxy vitamine D3. Ces composés s'avèrent utiles pour traiter les maladies osseuses et le psoriasis.

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