Phenyl pyrrole aminoguanidine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 207/32 (2006.01) A61K 31/402 (2006.01) A61P 25/00 (2006.01) C07D 207/34 (2006.01) C07D 207/36 (2006.01) C07D 207/38 (2006.01) C07D 207/40 (2006.01) C07D 207/42 (2006.01)

Patent

CA 2688485

The present invention relates to phenyl pyrrole aminoguanidine derivatives of the general formula (I): (I) including tautomeric forms thereof, wherein n is 1, 2 or 3; or a pharmaceutically acceptable salt thereof. The present invention further relates to the use of such phenyl pyrrole aminoguanidine derivatives for the treatment of diseases associated with the melanocortin receptors or related systems, e.g. the melanocyte stimulating hormones.

La présente invention concerne des dérivés de phényl pyrrole aminoguanidine de formule générale (I) : (I) y compris de formes tautomères de ceux-ci, n étant 1, 2 ou 3; ou un sel pharmaceutiquement acceptable de ceux-ci. La présente invention concerne également l'utilisation de dérivés de phényl pyrrole aminoguanidine pour le traitement de maladies associées aux récepteurs de la mélanocortine ou à des systèmes apparentés, p. ex. les hormones stimulant le mélanocyte.

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