Phenylserine derivatives and processes for preparing the same

Details Phenylserine derivatives and processes for preparing the same Phenylserine derivatives and processes for preparing the same

C - Chemistry, Metallurgy

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C07D 295/18 (2006.01) C07D 207/06 (2006.01) C07D 207/08 (2006.01) C07D 207/335 (2006.01) C07D 209/08 (2006.01) C07D 209/14 (2006.01) C07D 209/44 (2006.01) C07D 213/75 (2006.01) C07D 217/06 (2006.01) C07D 257/06 (2006.01) C07D 295/125 (2006.01) C07D 295/185 (2006.01) C07D 307/52 (2006.01) C07D 317/58 (2006.01) C07D 319/16 (2006.01) C07F 17/02 (2006.01) C07K 5/065 (2006.01)

Patent

CA 1226283

Abstract: The invention provides novel phenylserine derivatives of the formula: Image [I] and pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions, and a process for preparing the compounds. These phenylserine deri- vatives and their pharmaceutically acceptable acid addition salts inhibit the biosynthesis of leucotrienes and/or antagonistic activity against SRS-A and hence are useful for the phophylaxis and treatment of various allergic diseases (e.g. bronchial asthma, allergic. nasitis, urticaria), ischemic heart disease, ischemic encephalopathy, inflammation, and the like.

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