C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/6561 (2006.01) A61K 31/675 (2006.01)
Patent
CA 2195262
A phosphonate nucleotide compound having antiviral activity and is useful for an orally available and highly safe antiviral agent, which is represented by the following formula (I): Image wherein R1 represents hydrogen, a C1-C6 alkoxy, a halogen- substituted C1-C4 alkoxy, halogen, amino, or nitro; R2 and R3 independently represent hydrogen, a C1-C2 2 alkyl, an acyloxymethy, an acylthioethyl, or a halogen-substituted ethyl; R4 represents hydrogen, a C1-C4, alkyl, a C1-C4 hydroxyalkyl, or a halogen- substituted C1-C4, alkyl; and X represents carbon or nitrogen.
Kamiya Naohiro
Sekiya Kouichi
Takashima Hideaki
Ubasawa Masaru
Ueda Naoko
Dennison Associates
Mitsubishi Chemical Corporation
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