Phosphonosulfonate squalene synthetase inhibitor salts and...

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/38 (2006.01) A61K 31/66 (2006.01) C07F 9/40 (2006.01)

Patent

CA 2159850

New salt forms of the phosphonosulfonate squalene synthetase inhibitor Image are provided which include the calcium, the t- butylamine salt, t-octylamine salt and the dehydroabietylamine salt. These salts inhibit cholesterol biosynthesis and therefore are used in lowering serum cholesterol and in treating atherosclerosis.

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