Phthalazine compounds and therapeutic agents for erectile...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 237/34 (2006.01) A61K 31/50 (2006.01) C07D 237/28 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 409/14 (2006.01) C07D 411/14 (2006.01) C07D 451/06 (2006.01) C07D 471/08 (2006.01) C07D 491/04 (2006.01) C07D 491/08 (2006.01) C07D 491/10 (2006.01) C07D 498/08 (2006.01)

Patent

CA 2302943

Phthalazine derivatives represented by general formula (I) or pharmacologically acceptable salts thereof or hydrates of the same usable as remedies for erectile dysfunction, wherein R1 and R2 are the same or different and each represents halogeno, optionally halogenated alkyl or alkoxy, or cyano; X represents cyano, nitro, halogeno, optionally substituted hydroxyimino or optionally substituted heteroaryl; and Y represents heteroaryl, aryl, alkynyl, alkenyl, alkyl or cyclic amine.

L'invention concerne des dérivés de phtalazine de la formule générale (I) ou des sels pharmacologiquement acceptables desdits dérivés, ou des hydrates desdits dérivés pouvant être utilisés comme remèdes contre la dysérection. Dans ladite formule R1 et R2 sont identiques ou différents et représentent chacun halogéno, alkyle éventuellement halogéné ou alcoxy ou cyano; X est cyano, nitro, halogéno, hydroxyimino éventuellement substitué ou hétéroaryle éventuellement substitué; et Y est hétéroaryle, aryle, alkynyle, alcényle, alkyle ou amine cyclique.

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