C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01) C12N 9/12 (2006.01) C12N 9/22 (2006.01) C12N 15/09 (2006.01) C12N 15/85 (2006.01) C12N 15/90 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 40/02 (2006.01) C40B 50/06 (2006.01)
Patent
CA 2608481
The present invention relates to transgenic vertebrate, including mammalian, cells, whose genomes comprise one or more elements of the piggyBac family transposon system. Transgenic non-human vertebrates, including transgenic non- human mammals, whose genomes comprise one or more elements of the piggyBac family transposon system, are also provided. Methods of making and using the cells and animals of the invention, including applications in the medical, veterinary, and agricultural fields, are additionally provided. The present invention also relates to kits useful for practicing such methods.
La présente invention concerne des cellules de vertébré transgénique, y compris un mammifère, dont les génomes comprennent un ou plusieurs éléments du système transposon piggyBac. L'invention porte également sur des vertébrés non humains transgéniques, y compris des mammifères non humains transgéniques, dont les génomes comprennent un ou plusieurs éléments du système transposon de la famille piggyBac. Des procédés de fabrication et d'utilisation des cellules et des animaux de l'invention, y compris les applications dans les domaines médical, vétérinaire, et agricole, sont également décrits. La présente invention concerne aussi des nécessaires utiles pour la pratique de tels procédés.
Ding Sheng
Han Min
Li Gang
Wu Xiaohui
Xu Tian
Fudan University
Osler Hoskin & Harcourt Llp
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