A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/496 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2603360
The present invention relates to piperazine substituted cyclohexane-1,4- diamine compounds of Formula (I) and pharmaceutically acceptable forms thereof, as .alpha.1a/.alpha.1d adrenoreceptor modulators for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms. The present invention also relates to pharmaceutical compositions comprising said new compounds, new processes to prepare these new compounds and new uses as a medicine as well as methods of treatment.
L~invention concerne des composés de cyclohexane-1,4-diamine pipérazine-substitués de Formule (I) et leurs formes pharmaceutiquement acceptables, en tant que modulateurs de l~adrénorécepteur .alpha.1a/.alpha.1d pour le traitement de l~hypertrophie bénigne de la prostate et de la sténose urétrale. L~invention concerne également des compositions pharmaceutiques comprenant lesdits nouveaux composés, de nouveaux procédés de fabrication de ces nouveaux composés et de nouvelles utilisations en tant que médicaments ainsi que de nouvelles méthodes de traitement.
Chiu George
Connolly Peter J.
Li Shengjian
Liu Jingchun
Middleton Steven A.
Janssen Pharmaceutica N.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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