Piperidine derivatives as ccr5 antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 451/04 (2006.01) A61K 31/46 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2509711

The present invention relates to compounds of formula (I) or pharmaceutically acceptable derivatives thereof, useful in the treatment or prophylaxis of CCR5- related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

La présente invention porte sur des composés de formule (I) ou sur leurs dérivés acceptables d'un point de vue pharmaceutique, ces composés étant utiles dans le traitement ou la prophylaxie des maladies ou troubles liés à CCR5, par exemple, dans l'inhibition de la réplication du VIH, la prévention ou le traitement d'une infection provoquée par le VIH et dans le traitement du syndrome d'immunodéficience acquise (SIDA) en résultant.

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