C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.18, 195/1.
C12N 15/69 (2006.01) C12N 1/21 (2006.01) C12N 15/68 (2006.01) C12P 21/00 (2006.01)
Patent
CA 1313829
ABSTRACT OF THE DISCLOSURE A plasmid which carriers an inserted regulatable promoter at a position and in an orientation-permitting transcription from the promoter into the replication region. The replication region comprises a gene coding for a gene product which is positively needed for replication. Increased transcription from the regulatable promoter leads to an increased level of the gene product which is positively needed for replication. This increased level results in a plasmid replication rate which is higher than the host cell growth rate leading to a substantial increased or uncontrolled plasmid copy number. The subject plasmids may be used as cloning vectors for the insertion of foreign (e.g. eucaryotic) DNA coding for a desired polypeptide.
436866
Larsen Jens Erik Lõve
Light Janice Ann
Molin Soren
Mccarthy Tetrault Llp
Nycomed Danmark A/s
LandOfFree
Plasmids with conditional uncontrolled replication behaviour does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Plasmids with conditional uncontrolled replication behaviour, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Plasmids with conditional uncontrolled replication behaviour will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1273174