C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 65/329 (2006.01) A61K 31/7056 (2006.01) A61K 45/06 (2006.01) A61K 47/30 (2006.01) A61K 47/48 (2006.01) A61P 31/12 (2006.01) A61P 31/14 (2006.01) C07K 14/555 (2006.01) C07K 14/565 (2006.01) C07K 17/02 (2006.01) C08L 71/02 (2006.01) A61K 38/21 (2006.01)
Patent
CA 2473526
The biological activity of biologically active compounds and reduction of toxicity is addressed by the conjugation of a biologically active compound with an activated polyalkylene glycol having a moiety which covalently bonds to the compound. A pharmaceutical composition containing the polyalkylene glycol conjugate and a carrier, and a method of treating a patient by the administration of a composition with the polyalkylene glycol conjugate are described.
L'invention concerne des nouveaux composés de polyalkylène glycol et des méthodes d'utilisation de ces composés. L'invention concerne en particulier l'administration de composés comprenant un nouveau conjugué polyéthylène glycol, seuls ou combiné avec des agents antiviraux, pour le traitement d'infections virales telles que l'hépatite C chronique.
Baker Darren P.
Chen Ling Ling
Hess Donna M.
Lin Edward Y.
Lin Kochung
Biogen Idec Ma Inc.
Riches Mckenzie & Herbert Llp
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