Polyepitopic protein fragments of the e6 and e7 proteins of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/37 (2006.01) A61K 39/12 (2006.01) C07K 14/025 (2006.01) C07K 14/16 (2006.01) C07K 16/08 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2375627

The invention relates to the use of polyepitopic fragments of a determined protein in the production of medicaments for preventing or treating pathologies in which said protein is recognized by the cellular immune system. Said fragments are chosen from E6 and E7 HPV proteins. The invention also relates to polyepitopic proteinic fragments of E6 and E7 HPV proteins, a method for the production and the use thereof in the field of vaccination.

La présente invention a pour objet l'utilisation de fragments polyépitopiques d'une protéine déterminée pour la préparation de médicaments destinés à la prévention ou au traitement de pathologies dans lesquelles ladite protéine est reconnue par le système immunitaire cellulaire, lesdits fragments polyépitopiques étant choisis parmi ceux des protéines E6 et E7 de HPV. L'invention a également pour objet des fragments protéiques polyépitopiques des protéines E6 et E7 de HPV, leur procédé d'obtention, et leurs utilisations, notamment dans le domaine de la vaccination.

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