Polyethoxylated ascorbic acid derivatives as a novel...

Details Polyethoxylated ascorbic acid derivatives as a novel... Polyethoxylated ascorbic acid derivatives as a novel...

C - Chemistry, Metallurgy

07

D

C07D 307/62 (2006.01)

Patent

CA 2324306

Provided with a novel ascorbic acid derivative represented by the formula (I) and a method for preparing the same: (see figure I) wherein R1 and R2 are different from each other and, independently H or - CH2CH2-(O-CH2-CH2)n-OR3, wherein n is an integer from 2 to 400; and R; is a lower alkyl group having 1 to 10 carbon atoms. The novel ascorbic acid derivatives of this invention have excellent characteristics such as long-lasting anti-oxidation effect. high solubility in both water and organic solvents. and high stability in an aqueous solution. Furthermore, the novel ascorbic acid derivatives are useful for feed, food, cosmetic and pharmaceutical products due to their low toxicity and high thermal stability.

L'invention concerne de nouveaux dérivés d'acide ascorbique représentés par la formule (I) dans laquelle R1 et R2, qui sont différents, représentent un atome d'hydrogène ou (CH2CH2O)nCH2CH2OR3 (dans laquelle n est un entier de 1 à 399; R3 représente un groupe alkyle inférieur pouvant posséder de 1 à 10 atomes de carbone) et leur préparation. Elle concerne, de plus, de nouveaux dérivés d'acide ascorbique exerçant des effets antioxydants très stables pendant une durée prolongée, qui sont particulièrement solubles dans l'eau et, également, dans la plupart des solvants organiques. Le domaine d'application de l'invention s'étend à l'alimentation animale, aux produits alimentaires de consommation humaine, aux cosmétiques et aux produits pharmaceutiques.

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