Polymer complexes of a sugar response type

Details Polymer complexes of a sugar response type Polymer complexes of a sugar response type

A - Human Necessities

61

K

260/212, 400/511

A61K 47/48 (2006.01) A61K 47/30 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2027930

The present invention provides a polymer complex of a sugar response type having boronic acid groups in the polymer. Medicines may be contained or linked, preferably, the medicines have hydroxy groups. The polymer having boronic acid groups and the medicine having hydroxy groups may be linked by boronic acid ester bonds. The complex may also comprises polymers having boronic acid groups and polymers having hydroxy groups, and these polymers may be cross-linked.

L'invention consiste en un complexe polymérique réagissant à la concentration de sucres et comportant des groupements acide boronique. Les médicaments peuvent être contenus dans le complexe polymérique ou y être liés et ont, de préférence, des groupements hydroxy. Le polymère ayant des groupements acide boronique et le médicament ayant des groupements hydroxy peuvent être liés par les liaisons ester de l'acide boronique. Le complexe peut également comprendre des polymères ayant des groupements acide boronique et des polymères ayant des groupements hydroxy; en outre, ces polymères peuvent être réticulés.

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