Polymers for delivery of nucleic acids

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 9/16 (2006.01) A61K 47/24 (2006.01) C08J 9/00 (2006.01) C12N 15/88 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2335460

The present invention relates to compositions and methods for delivery of nucleic acids. In particular, the invention provides a polymeric delivery formulation including a nucleic acid to be transfected into a host cell, formulated in a biodegradable polymer having phosphorous-based linkages.

La présente invention concerne des compositions et des méthodes d'administration intramusculaire d'acides nucléiques. L'invention concerne notamment une formulation d'administration polymère comprenant un acide nucléique à transfecter dans une cellule hôte, préparé sous la forme d'un polymère biodégradable à liaisons phosphore.

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