C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/445 (2006.01) A61P 37/00 (2006.01) C07D 211/62 (2006.01) C07D 235/14 (2006.01)
Patent
CA 2484460
Polymorph 1 of 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazole-2-yl]-1- piperidinyl] ethyl]-.alpha..alpha.-dimethyl-benzeneacetic acid of formula (I) is described, procedures for its preparation, pharmaceutical formulae containing polymorph 1 and the use of polymorph 1 to treat allergic reactions and pathological processes mediated by histamine in mammals such as man. (See Formula I)
L'invention concerne le polymorphe 1 de l'acide 4-[2-[4-[1-(2-éthoxyéthyl)-1H-benzimidazol-2-il]-1-pipéridinyl]éthyl]- alpha , alpha -diméthyl-benzénoacétique de formule (I), ses procédés de préparation, des formulations pharmaceutiques contenant le polymorphe 1 et l'utilisation du polymorphe 1 dans le traitement de réactions allergiques et de processus pathologiques régulés par l'histamine chez les mammifères tels que l'être humain.
Blanco Fuente Haydee
Bordell Martin Maravillas
Canal Mori Gonzalo
Lucero de Pablo Maria Luisa
Mosquera Pestana Ramon
Faes Farma S.a.
Fetherstonhaugh & Co.
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