C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 231/22 (2006.01) C07C 233/52 (2006.01)
Patent
CA 2710484
The present invention relates to polymorphic forms of Oseltamivir phosphate, especially the (3R,4R,5S) -5-amino-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-ene-carboxylic acid ethyl ester phosphate, which is a potent inhibitor of viral neuraminidase.
La présente invention porte sur des formes polymorphes de phosphate d'Oseltamivir, en particulier du phosphate d'ester éthylique d'acide (3R,4R,5S)-5-amino-4-acétylamino-3-(1-éthyl-propoxy)-cyclohex-1-ène-carboxylique, qui est un inhibiteur puissant de la neuraminidase virale.
Bubendorf Andre
Goldbach Pierre
Grassmann Olaf
Hennig Michael
Sauer Ines
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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