Polymorphic forms of oseltamivir phosphate

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 231/22 (2006.01) C07C 233/52 (2006.01)

Patent

CA 2710484

The present invention relates to polymorphic forms of Oseltamivir phosphate, especially the (3R,4R,5S) -5-amino-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-ene-carboxylic acid ethyl ester phosphate, which is a potent inhibitor of viral neuraminidase.

La présente invention porte sur des formes polymorphes de phosphate d'Oseltamivir, en particulier du phosphate d'ester éthylique d'acide (3R,4R,5S)-5-amino-4-acétylamino-3-(1-éthyl-propoxy)-cyclohex-1-ène-carboxylique, qui est un inhibiteur puissant de la neuraminidase virale.

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