Polymorphs of donepezil hydrochloride and process for...

Details Polymorphs of donepezil hydrochloride and process for... Polymorphs of donepezil hydrochloride and process for...

C - Chemistry, Metallurgy

07

D

C07D 211/32 (2006.01) A61K 31/445 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2516108

Donepezil hydrochloride, 1-benzyl-4-[(5,6- dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride, is provided here in the form of three polymorphs which are stable against heat and humidity in pharmaceutical use. They can be industrially produced. They are specified by peaks in X-ray powder diffraction pattern and absorption peaks in infrared absorption spectra in potassium bromide.

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