C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/56 (2006.01) A61K 38/12 (2006.01) C07K 1/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2123921
ABSTRACT The invention relates to novel polypeptide compounds having the general formula: Image [ I ] wherein R1 is a hydrogen atom, R2 is an acyl group, R3 is a hydroxy or acyloxy group, R4 is a hydroxy or hydroxysulfonyloxy group, R5 is a hydrogen atom or a lower alkyl group which is optionally substituted with a hydroxy, acyl, di(lower)alkylamino or cyclic amino group, and R6 is a hydrogen atom, a hydroxy or acyl (lower) alkylthio group, and pharmaceutically acceptable salts thereof. The polypeptide compounds of formula [I] and their pharmaceutically acceptable salts are useful for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms.
Ohki Hidenori
Takasugi Hisashi
Tomishima Masaki
Yamada Akira
Fujisawa Pharmaceutical Co. Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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