Polypeptides and nucleic acids encoding same

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 38/48 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/555 (2006.01) C07K 14/705 (2006.01) C12N 9/64 (2006.01) C12N 15/57 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2400360

The present invention provides isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

L'invention concerne de nouveaux polynucléotides isolés NOVX et des polypeptides codés par ces polynucléotides NOVX. Elle concerne également les anticorps qui se fixent de façon immunospécifique à un polypeptide NOVX ou à tout dérivé, toute variante, tout mutant ou tout fragment de ce polypeptide NOVX, de ce polynucléotide ou de cet anticorps. Elle concerne, de plus, des procédés consistant à mettre en application ce polypeptide NOVX, ce polynucléotide et cet anticorps afin de détecter et de traiter une variété importante d'états pathologiques, ainsi que d'autres utilisations.

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