Polypeptides and processes for the synthesis thereof

Details Polypeptides and processes for the synthesis thereof Polypeptides and processes for the synthesis thereof

C - Chemistry, Metallurgy

07

K

530/7.06, 530/5.

C07K 7/06 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1126261

ABSTRACT The invention provides Polypeptide compounds having the sequence X-Gln-Gly-Gly-Y in which Y represents -Ser-Asn and X represents Ser-, Lys-Ser-, Ala-Lys-Ser-, Glx-Ala-Lys-Ser-; G1x representing PyroGlu or Gln; and when X represents G1x-Ala-Lys-Ser-, Y may in addition represent -Ser; as well as their derivatives comprising 1 or 2 modified amino acids, with the exception of the unmodified compound PyroGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser- Asn.

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