Polyunsaturated fatty acid monoglycerides, derivatives, and...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 219/08 (2006.01) A61K 31/164 (2006.01) A61K 31/232 (2006.01) A61K 31/357 (2006.01) A61K 31/39 (2006.01) A61K 31/661 (2006.01) A61K 31/665 (2006.01) A61P 35/00 (2006.01) C07C 69/587 (2006.01) C07C 233/20 (2006.01) C07D 317/24 (2006.01) C07D 327/10 (2006.01) C07F 9/113 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 2672513

The invention emcompasses polyunsaturated fatty acid monoglycerides and derivatives thereof, having the formulae (I), (II), (III) and (IV), pharmaceutically acceptable salts thereof, compositions thereof and processes of preparing said compounds. These compounds can be useful as cancer chemopreventive agents, cancer treating agents, or radioenhencers for radiotherapy of cancer, or for inhibiting tumor growth or cell proliferation, or reducing tumor growth.

L'invention porte sur des monoglycérides d'acides gras polyinsaturés et des dérivés de ceux-ci, ayant les formules (I), (II), (III) et (IV), sur de sels pharmaceutiquement acceptables de ceux-ci, sur des compositions de ceux-ci et sur des procédés de préparation desdits composés. Ces composés peuvent être utiles comme agents chimiopréventifs du cancer, agents de traitement du cancer ou radio amplificateurs pour la radiothérapie du cancer ou pour l'inhibition de la croissance tumorale ou de la prolifération cellulaire ou pour la réduction de la croissance tumorale.

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