Porcine islets cultured with porcine sertoli cells for...

Details Porcine islets cultured with porcine sertoli cells for... Porcine islets cultured with porcine sertoli cells for...

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61K 35/39 (2006.01) A61L 27/38 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01)

Patent

CA 2529573

Aggregates and their method of preparation suitable for implantation into a recipient in order to produce insulin in vivo. The methods involve culturing islet cells isolated from the pancreas of donor piglets with isolated Sertoli cells from the testes of donor piglets. A preferred period of culturing is 5 days and may be followed by a purification procedure.

La présente invention a trait à des amas et leur procédé de préparation destinés à l'implantation chez un receveur en vue de la production d'insuline in vivo. Les procédés comprennent la culture de cellules sécrétrices d'insuline isolées dérivées du pancréas de porcelets donneurs avec des cellules de Sertoli isolées dérivées des testicules de porcelets donneurs. Une durée préférée de culture est de 5 jours et peut être suivie par un procédé d'épuration.

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