Powdered protein compositions and methods of making same

Details Powdered protein compositions and methods of making same Powdered protein compositions and methods of making same

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) A61K 38/02 (2006.01) A61K 39/00 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2711984

A method for preparing a protein or peptide powder is provided that includes spray drying a solution including more than, e.g., about 50 mg/mL of a protein or peptide (e.g., an antibody or antigen binding protion thereof), and at least one excipient. Also provided are stable powdered compositions including a protein and an excipient having less than, e.g., about 6% residual moisture.

La présente invention concerne un procédé de préparation d'une poudre de protéine ou de peptide. Ledit procédé inclut le séchage par atomisation d'une solution comprenant par exemple plus de 50 mg/mL environ d'une protéine ou d'un peptide (par exemple une portion de celle-ci liée à un antigène ou à un anticorps), et au moins un excipient. L'invention concerne également des compositions pulvérisées stables incluant une protéine et un excipient présentant par exemple moins de 6 % environ d'humidité résiduelle.

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