C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 9/00 (2006.01) A61K 31/56 (2006.01) A61K 31/57 (2006.01) A61K 31/575 (2006.01) A61K 31/58 (2006.01) A61P 25/22 (2006.01) C07J 5/00 (2006.01) C07J 7/00 (2006.01) C07J 13/00 (2006.01) C07J 53/00 (2006.01) C07J 71/00 (2006.01)
Patent
CA 2196690
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a pregnane or cholane steroid, or a pharmaceutical composition containing a vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. Other embodiments of the invention include pharmaceutical compositions containing the steroids.
Procédé de modification de la fonction hypothalamique chez un individu consistant à lui administrer par voie nasale une vomérophérine, c.-à-d. un stéroïde du type pregnane ou cholane ou une préparation pharmaceutique la contenant de manière à ce que la vomérophérine se fixe à un récepteur neuroépithélial spécifique. Le ou lesdits stéroïdes sont de préférence administrés sous forme de préparation pharmaceutique comportant un ou plusieurs excipients compatibles. D'autres variantes de l'invention portent sur des préparations pharmaceutiques contenant lesdits stéroïdes.
Adams Nathan William
Berliner David L.
Jennings-White Clive L.
Dennison Associates
Pherin Corporation
Pherin Pharmaceuticals Inc.
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