Preparation for injection containing a lipid a analog and...

Details Preparation for injection containing a lipid a analog and... Preparation for injection containing a lipid a analog and...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 47/02 (2006.01) A61K 9/19 (2006.01)

Patent

CA 2259520

The present invention provides a preparation for injection containing a lipid A analog and a process for preparing the same. A preparation for injection prepared by dissolving a lipid A analog or a pharmacologically acceptable salt thereof in an alkaline aqueous solution, at an elevated temperature if necessary, and then adding a buffer thereto, and a process for preparing the same.

Cette invention se rapporte à des produits pour injection contenant des analogues de lipides A ou des sels pharmacologiquement acceptables de ces analogues ainsi qu'à un procédé de préparation de ces produits. L'invention se rapporte tout particulièrement à des produits pour injection que l'on prépare en dissolvant un analogue de lipide A ou un sel pharmacologiquement acceptable d'un tel analogue dans une solution alcaline aqueuse, si nécessaire en chauffant, et en ajoutant un tampon à la solution obtenue, ainsi qu'au procédé de préparation correspondant.

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