Preparation of biologically derived fluids for biomarker...

Details Preparation of biologically derived fluids for biomarker... Preparation of biologically derived fluids for biomarker...

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2554575

Methods and kits for preparing biologically derived fluids for subsequent biomarker analysis by mass spectrometry are provided. Using a buffer comprising salt in the range of 0.1% to 2.0%, a chaotropic agent, a reducing agent and a volatile organic acid, the sample is prepared for solid phase adsorption. Thus, the loss of components unbound to the active surface is limited.

La présente invention se rapporte à des procédés et à des kits permettant de préparer des fluides d'origine biologique en vue d'une analyse ultérieure de biomarqueurs par spectrométrie de masse.

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