Preparation of detoxified e. coli neurotoxin and obtained...

Details Preparation of detoxified e. coli neurotoxin and obtained... Preparation of detoxified e. coli neurotoxin and obtained...

A - Human Necessities

61

K

167/135

A61K 39/108 (2006.01)

Patent

CA 1188220

ABSTRACT Detoxified but still immunogenic E. coli neurotoxin is prepared by bringing E. coli neurotoxin into contact with glutaraldehyde in mild operative conditions, the reaction being stopped where no more than 90 % of the neurotoxin are inactivated. The obtained detoxified neurotoxin is valuable for immunizing piglets against oedema disease.

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