Preparation of difluorobenzenes containing electron...

Details Preparation of difluorobenzenes containing electron... Preparation of difluorobenzenes containing electron...

C - Chemistry, Metallurgy

07

C

C07C 17/20 (2006.01) C07C 25/13 (2006.01) C07C 255/50 (2006.01)

Patent

CA 2003919

3,4-Difluoro substituted benzenes are prepared by reacting 3,4-dihalo substituted benzenes with an effective amount of KF or CsF, in a polar aprotic solvent, at an elevated temperature, under substantially anhydrous conditions. The product can be removed as it is formed or the reaction may be run at the autogenous pressures generated by the reaction mixture in a sealed reactor.

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