C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 25/28 (2006.01) C07K 16/46 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2678963
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
L'invention concerne des agents et des procédés améliorés pour le traitement de maladies associées avec les maladies synucléinopathiques, notamment les corps de Lewy d'alpha-synucléine dans le cerveau d'un patient. De tels procédés comprennent l'administration d'agents qui induisent une réponse immunogène bénéfique contre le corps de Lewy. Les procédés sont particulièrement utiles pour le traitement prophylactique et thérapeutique de la maladie de Parkinson.
Buttini Manuel J.
Chilcote Tamie J.
Games Kate Dora
Masliah Eliezer
Rockenstein Edward
Elan Pharmaceuticals Inc.
Gowling Lafleur Henderson Llp
The Regents Of The University Of California
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