C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61P 25/28 (2006.01) A61P 37/04 (2006.01) C07K 16/46 (2006.01) C12N 5/16 (2006.01)
Patent
CA 2616047
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha- synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
Cette invention concerne des agents améliorés et des méthodes de traitement de maladies associées à des maladies synucléinopathiques, dont les corps de Lewy de l'alpha-synucléine dans le cerveau d'un patient. Ces méthodes consistent à administrer des agents induisant une réponse immunogène contre le corps de Lewy. Les méthodes de l'invention sont particulièrement utiles pour le traitement prophylactique ou thérapeutique de la maladie de Parkinson.
Buttini Manuel J.
Chilcote Tamie J.
Games Dora Kate
Masliah Eliezer
Rockenstein Edward
Elan Pharmaceuticals Inc.
Smart & Biggar
The Regents Of The University Of California
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