"prionins", highly specific markers for noninvasive...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2206774

Proteins expressed from within the prion protein genes of all animals and humans, "prionins", against which reagents can be prepared for accurate pre-symptomatic diagnosis, for detecting latent TSE, for detecting TSE contamination of food, blood and blood products and for therapeutic treatment of Bovine spongiform encephalopathy (BSE) in cows, Scrapie disease in sheep and Creutzfeldt-Jakob syndrome in humans, are revealed.

Divulgation de protéines exprimées de l'intérieur des gènes des protéines prions de tous les animaux et humains, les « prionines », contre lesquelles des réactifs peuvent être préparés pour un diagnostic présymptomatique exact, aux fins de la détection d'une EST latente, de la contamination des aliments, du sang et des produits sanguins par une EST et pour le traitement thérapeutique de l'encéphalopathie spongiforme bovine (ESB) chez les vaches, de la tremblante chez les moutons et du syndrome de Creutzfeldt-Jakob chez les humains.

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