Process for determination of glycosylated hemoglobin and...

G - Physics – 01 – N

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150/11, 150/3

G01N 33/66 (2006.01) G01N 33/72 (2006.01)

Patent

CA 1170552

Abstract of the Disclosure An improved process for determining glycosylated hemoglobin wherein the contribution of unstable glucose-aldimine-hemoglobin compounds to the HbA1 value is substantially eliminated by reacting the hemolysate with a primary amine and a hydrazine compound and thereafter subjecting the hemolysate to chromatography. The process enables reliable evaluation of the HbA1 value as a long-term parameter in diabetic metabolism control.

396974

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