C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/474, 260/646
C07C 172/00 (1985.01)
Patent
CA 1254225
ABSTRACT Novel cyclovitamin compounds of the formula Image wherein X is hydrogen, hydroxy, O-acyl or O-aromatic acyl, Z is hydrogen, lower alkyl, acyl or aromatic acyl and R is hydrogen or lower alkyl or a side chain of the general for- mula Image are prepared from the corresponding compounds of the formula Image via the C-3-sulfonic acid ester and then solvolyzing the ester in an alcoholic or aqueous solvent. The compounds are useful as intermediates in the preparation of the corres- ponding l.alpha.-hydroxylated vitamin D compounds which have vitamin D-like activity.
425450
Deluca Hector F.
Hamer David E.
Paaren Herbert E.
Schnoes Heinrich K.
Osler Hoskin & Harcourt Llp
Wisconsin Alumni Research Foundation
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