Process for preparing...

Details Process for preparing... Process for preparing...

C - Chemistry, Metallurgy

07

H

C07H 17/00 (2006.01) C07D 413/12 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2383409

The invention relates to processes for preparing compounds of formula 1 (see formula 1) wherein R3 is -CH2NR8R15, R8 is C1-C10 alkyl and R15 is H or C1-C10 alkyl, and to pharmaceutically acceptable salts thereof, as well as intermediates useful in such processes. The process includes a reaction of a compound of the formula 2 (see formula 2) with an amine HNR8R15 in isopropanol at a temperature of at least 40°C. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections.

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