Process for preparing [2-(2,3-dihydrobenzofuran- or...

Details Process for preparing [2-(2,3-dihydrobenzofuran- or... Process for preparing [2-(2,3-dihydrobenzofuran- or...

C - Chemistry, Metallurgy

07

D

C07D 307/86 (2006.01) C07C 47/548 (2006.01) C07D 307/94 (2006.01) C07D 317/20 (2006.01)

Patent

CA 2646346

ABSTRACT. PROCESS FOR PREPARING [2-(2,3-DIHYDROBENZOFURAN- OR BENZOFURAN-7-YLOXY)ETHYL]-(3-CYCLOPENT-1-YLBENZYL)AMINE DERIVATIVES AND SYNTHESIS INTERMEDIATE The invention relates to a process for preparing compounds of general formula (see ~abstract~ paper version) in which: - (a) is a single or double bond; - W is a CH, CH2, CHCH3, CCH3 or C(CH3)2 group or a C(CH2)2 group (i.e. a carbon atom bearing two methylene groups linked to one another so as to form a spirocyclopropane unit), with the proviso, however, that, when (a) is a double bond, then W is exclusively a CH or CCH3 group and that, when (a) is a single bond, then W is exclusively a CH2, CHCH3, C(CH3)2 or C(CH2)2 group.

ABREGE PROCEDE DE PREPARATION DE DÉRIVÉS [2-(2,3-DIHYDRO-BENZOFURAN- OU BENZOFURAN-7-YLOXY)-ETHYL]-(3-CYCLOPENTEN-1-YL-BENZYL)-AMINES ET INTERMEDIAIRE DE SYNTHESE L'invention concerne un procédé de préparation de composés de formule générale (Voir "abrégé" version papier) dans lequel : - (a) représente une liaison simple ou double; - W représente un groupe CH, CH2, CHCH3, CCH3, C(CH3)2, un groupe C(CH2)2 (i.e., un atome de carbone portant deux groupes méthylènes liés entre eux de manière ô former un motif spiro-cyclopropane) avec la réserve, toutefois, que lorsque (a) est une liaison double alors W représente exclusivement un groupe CH ou CCH3 et que, lorsque (a) est une liaison simple, alors W représente exclusivement un groupe CH2, CHCH3, C(CH3)2 ou C(CH2)2

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