Process for preparing 3,4-difluoroaniline

Details Process for preparing 3,4-difluoroaniline Process for preparing 3,4-difluoroaniline

C - Chemistry, Metallurgy

07

C

C07C 211/52 (2006.01) C07C 209/22 (2006.01) C07C 209/74 (2006.01) C07C 239/10 (2006.01)

Patent

CA 2080596

2080596 9117138 PCTABS00008 A process for preparing 3,4-difluoroaniline comprising reacting 1-hydroxylamine-3-fluorobenzene with anhydrous hydrogen fluoride in the absence of oxygen. This compound is useful as a starting material for preparation of quinolone antibacterials. 3-Fluoro-1-hydroxylamine may be prepared by hydrogenating 3-fluoro-1-nitrobenzene.

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