Process for preparing bicyclic compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) C07D 207/22 (2006.01)

Patent

CA 2604384

The present invention relates to a process for preparing compounds of formula (IA), which are potent and specific antagonists of corticotropin-releasing factor (CRF) receptors, from intermediate compounds of formula (I), by a coupling reaction catalysed by copper wherein the substituents are as defined in the claims .

L'invention concerne un procédé pour préparer des composés de formule (IA). Ces composés sont puissants et sont des antagonistes spécifiques des récepteurs du facteur de libération de corticotropine (CRF), obtenus à partir de composés intermédiaires de formule (I), par une réaction de liaison catalysée par du cuivre dans laquelle les substituants sont définis dans les revendications.

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