C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) C07D 207/22 (2006.01)
Patent
CA 2604384
The present invention relates to a process for preparing compounds of formula (IA), which are potent and specific antagonists of corticotropin-releasing factor (CRF) receptors, from intermediate compounds of formula (I), by a coupling reaction catalysed by copper wherein the substituents are as defined in the claims .
L'invention concerne un procédé pour préparer des composés de formule (IA). Ces composés sont puissants et sont des antagonistes spécifiques des récepteurs du facteur de libération de corticotropine (CRF), obtenus à partir de composés intermédiaires de formule (I), par une réaction de liaison catalysée par du cuivre dans laquelle les substituants sont définis dans les revendications.
Bacchi Sergio
Delpogetto Monica
Guelfi Simone
Perboni Alcide
Ribecai Arianna
Gowling Lafleur Henderson Llp
Neurocrine Biosciences Inc.
Sb Pharmco Puerto Rico Inc.
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