Process for preparing cycloalkyl-substituted piperazine...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/14 (2006.01)

Patent

CA 2735560

The present invention relates to a process for preparing compounds of the general formula (I) in which m, n, o, R1, R2 and R3 are each defined as mentioned below, the enantiomers thereof and the diastereomers thereof, which are particularly sui-table for preparing compounds of the general formula (II) in which m, o, R1, R2, R3 and R4 are each defined as mentioned below. The compounds of the general formula (II) possess B1-antagonistic properties.

La présente invention concerne un procédé de fabrication de composés de formule générale (I) dans laquelle m, n, o, R1, R2 et R3 sont définis tels quindiqué ci-après, leurs énantiomères et leurs diastéréoisomères, qui sont particulièrement appropriés pour la fabrication de composés de formule générale (II) dans laquelle m, o, R1, R2, R3 et R4 sont définis tels quindiqué ci-après. Les composés de formule générale (II) présentent des propriétés dantagonistes de B1.

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