Process for preparing l(-)-carnitine chloride from 3,...

Details Process for preparing l(-)-carnitine chloride from 3,... Process for preparing l(-)-carnitine chloride from 3,...

C - Chemistry, Metallurgy

12

P

260/369.1, 195/1

C12P 13/04 (2006.01) C12P 17/02 (2006.01) C12P 41/00 (2006.01)

Patent

CA 1309683

ABSTRACT OF THE DISCLOSURE L(-)-carnitine is useful as a eutrophyic agent and as cardioprotecting agent for the treatment of myocardial ischemias, angina pectoris, and sclerosis of the myocardium. It has the following formula: Image (I) It may be produced much more simply than hitherto from esters of R(+)-3,4-epoxybutyric acid. The R(+) enantiomers of the esters (themselves useful intermediates) are obtained by asymmetrical enzymatic hydrolysis of certain esters of the racemic 3,4-epoxybutyric acid.

532034

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