Process for preparing spirolaxine and spirolaxine methyl ether

Details Process for preparing spirolaxine and spirolaxine methyl ether Process for preparing spirolaxine and spirolaxine methyl ether

C - Chemistry, Metallurgy

12

P

C12P 17/18 (2006.01)

Patent

CA 2214871

Processes for preparing spirolaxine and spirolaxine methyl ether, the compounds of formulas (I) and (II) respectively, comprising fermenting fungi selected from the group consisting of Sporotrichum pruinosum FD 29585, ATCC 74327; Sporotrichum pruinosum FD 29454, ATCC 74329; Sporotrichum pruinosum FD 29586, ATCC 74328; and Phanerochaete chrysosporium LN 3576, ATCC 74326. This invention also relates to a process for preparing spirolaxine comprising fermenting Sporotrichum pruinosum FD 29458, ATCC 74330.

La présente invention décrit les procédés de préparation de la spirolaxine et de l'éther de méthyle de spirolaxine, les composés respectivement de formule (I) et (II), consistant à fermenter des champignons choisis dans le groupe contenant le Sporotrichum pruinosum FD 29585, ATCC 74327; le Sporotrichum pruinosum FD 29454, ATCC 74329; le Sporotrichum pruinosum FD 29586, ATCC 74328; et le Phanerochaete chrysosporium LN 3576, ATCC 74326. Cette invention se rapporte également à un procédé de préparation de la spirolaxine consistant en la fermentation du Sporotrichum pruinosum FD 29458, ATCC 74330.

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